Manchester United won 10 and lost none of the 11 Barclays Premier League meetings with Stoke City until the Potters 2-1 victory at the Britannia Stadium in February.
Stoke have lost their last 11 away games against Manchester United in all competitions.
Robin van Persie has netted one goal in each of his four Premier League games against the Potters in a Manchester United shirt.
Overall, Robin van Persie has scored 10 goals in nine Premier League appearances against Stoke.
Stoke have not won consecutive games against the Red Devils in all competitions since February 1953.
Peter Crouch’s goal at Old Trafford last season was his first in nine Premier League games at the venue.
Wayne Rooney has scored in nine of his last 13 matches for England and Manchester United combined (10 goals).
Mark Hughes played 467 times for Manchester United in all competitions – the all-time 14th highest appearance maker for the club.
Hughes has already won a Premier League game as opposition manager at Old Trafford, when his Blackburn side defeated the Red Devils 2-1 in September 2005 (L7 D1 of the other eight trips there).
Manchester United have the opportunity to win four consecutive Premier League games for only the second time since the departure of Sir Alex Ferguson (after four wins in Dec 2013).