The defending champions face Chelsea, Liverpool and Manchester City in their first five league games.
“This will just really focus the guys and when we come back into pre-season we know we have to hit the ground running,” the defender told the BBC.
“This could be a blessing in disguise for the new manager and for the squad.”
United begin the defence of their Premier League title away at Swansea on the opening weekend before Jose Mourinho’s Chelsea visit Old Trafford.
Moyes’s side then go to Anfield to face Liverpool before hosting Crystal Palace and then making the short trip to the Etihad Stadium for a derby with rivals City.
Ferdinand added: “We don’t think about the reaction if we start badly. We expect the results to go our way and to do well.
“We have a hard run of games but that is part and parcel of being a top footballer, you have to be ready at all times.
“If we finish that run of five or six games at the beginning of the season and we’re in good shape, who knows what is possible.”
17 August: Swansea (away)
24 August: Chelsea (home)
31 August: Liverpool (away)
14 September: Crystal Palace (home)
21 September: Manchester City (away)